CD38hiCD19dim cells in lymph nodes predict favorable prognosis in patients with stage III melanoma receiving adjuvant PD-1-blockade

BackgroundAdjuvant immune checkpoint inhibitors (ICI) have improved survival in stage III cutaneous melanoma, yet many patients do not benefit. The tumor microenvironment is pivotal for durable responses; defining cellular composition can pinpoint immune components promoting anti-tumor activity and...

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Hauptverfasser:	Ieva Ailte, Sudhir Kumar Chauhan, Lina Prasmickaite, Assia V. Bassarova, Amanda Poissonnier, Marike Feenstra, Marta Nyakas, Bjarne Johannessen, Truls Ryder, Robert Hermann, Lars Frich, Arild Holth, Else Marit Inderberg, Henrik Jespersen, Vivi Ann Flørenes, Jon Amund Kyte, Gunhild M. Mælandsmo, Eivind Valen Egeland
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-05-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	CD103+PD-1+CD8+ T cells CD38hiCD19dim immune checkpoint inhibitors PD1-blockade plasmablast-like cells stage III melanoma
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1815008/full
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