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Microenvironment in neuroblastoma: isolation and characterization of tumor-derived mesenchymal stromal cells

Abstract Background It has been proposed that mesenchymal stromal cells (MSCs) promote tumor progression by interacting with tumor cells and other stroma cells in the complex network of the tumor microenvironment. We characterized MSCs isolated and expanded from tumor tissues of pediatric patients d...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Gloria Pelizzo, Veronica Veschi, Melissa Mantelli, Stefania Croce, Vincenzo Di Benedetto, Paolo D’Angelo, Alice Maltese, Laura Catenacci, Tiziana Apuzzo, Emanuela Scavo, Antonia Moretta, Matilde Todaro, Giorgio Stassi, Maria Antonietta Avanzini, Valeria Calcaterra
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-11-01
Schriftenreihe:BMC Cancer
Schlagworte:
Neuroblastoma
Mesenchymal stromal cells
Microenvironment
Stemness
EMT
Children
Online-Zugang:http://link.springer.com/article/10.1186/s12885-018-5082-2
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