PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment

Here the authors show that a Polycomb Repressive Complex 1 (PRC1) containing PCGF1 prevents excessive loading of transcriptional activators and chromatin remodelers on nascent DNA, allowing proper deposition of nucleosomes immediately after the passage of the DNA replication fork to optimize downstr...

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Bibliografiske detaljer

Principais autores:	Junichiro Takano, Shinsuke Ito, Yixing Dong, Jafar Sharif, Yaeko Nakajima-Takagi, Taichi Umeyama, Yong-Woon Han, Kyoichi Isono, Takashi Kondo, Yusuke Iizuka, Tomohiro Miyai, Yoko Koseki, Mika Ikegaya, Mizuki Sakihara, Manabu Nakayama, Osamu Ohara, Yoshinori Hasegawa, Kosuke Hashimoto, Erik Arner, Robert J. Klose, Atsushi Iwama, Haruhiko Koseki, Tomokatsu Ikawa
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2022-11-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-022-34856-8
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