Cepharanthine suppresses APC-mutant colorectal cancers by down-regulating the expression of β-catenin
Abstract The aberrant activation of the Wnt/β-catenin signaling pathway is closely associated with the development of various carcinomas, especially colorectal cancers (CRCs), where adenomatous colorectal polyposis (APC) mutations are the most frequently observed, which limits the anti-tumor efficie...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SpringerOpen
2024-02-01
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| Schriftenreihe: | Natural Products and Bioprospecting |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1007/s13659-024-00443-1 |
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