CRISPR/Cas-based CAR-T cells: production and application
Abstract Chimeric antigen receptor T cell (CAR-T) therapy has revolutionized the treatment approach for cancer, autoimmune disease, and heart disease. The integration of CAR into T cells is typically facilitated by retroviral or lentiviral vectors. However, the random insertion of CARs can lead to i...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2024-05-01
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| coleção: | Biomarker Research |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s40364-024-00602-z |
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