Study on the synthesis, physicochemical properties and transdermal absorption of scutellarein prodrugs
Abstract In this research, we aimed to improve the lipid solubility and transdermal absorbability of scutellarein through a prodrug strategy, and then improve its efficacy for treating psoriasis. Firstly, we designed and synthesized 19 prodrugs of scutellarein, including AC (alkylcarbonyl), AAC (alk...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2025-12-01
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| Edice: | Scientific Reports |
| Témata: | |
| On-line přístup: | https://doi.org/10.1038/s41598-025-03502-w |
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