DeepRepeat: direct quantification of short tandem repeats on signal data from nanopore sequencing

Abstract Despite recent improvements in basecalling accuracy, nanopore sequencing still has higher error rates on short-tandem repeats (STRs). Instead of using basecalled reads, we developed DeepRepeat which converts ionic current signals into red-green-blue channels, thus transforming the repeat de...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Li Fang, Qian Liu, Alex Mas Monteys, Pedro Gonzalez-Alegre, Beverly L. Davidson, Kai Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2022-04-01
Serie:	Genome Biology
Soggetti:	Short tandem repeat Nanopore sequencing Deep learning Telomeric repeat
Accesso online:	https://doi.org/10.1186/s13059-022-02670-6
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!