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Transcriptional repression of the oncofetal LIN28B gene by the transcription factor SOX6

Abstract The identification of regulatory networks contributing to fetal/adult gene expression switches is a major challenge in developmental biology and key to understand the aberrant proliferation of cancer cells, which often reactivate fetal oncogenes. One key example is represented by the develo...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Valentina Pastori, Gianluca Zambanini, Elisabetta Citterio, Tamina Weiss, Yukio Nakamura, Claudio Cantù, Antonella Ellena Ronchi
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2024-05-01
Цуврал:Scientific Reports
Онлайн хандалт:https://doi.org/10.1038/s41598-024-60438-3
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