Power-Doppler-based NH002 microbubble sonoporation with chemotherapy relieves hypoxia and enhances the efficacy of chemotherapy and immunotherapy for pancreatic tumors

Abstract Pancreatic ductal adenocarcinoma (PDAC) poses challenges due to late-stage diagnosis and limited treatment response, often attributed to the hypoxic tumor microenvironment (TME). Sonoporation, combining ultrasound and microbubbles, holds promise for enhancing therapy. However, additional pr...

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Detalhes bibliográficos

Principais autores:	Sheng-Yan Wu, Chung-Hsin Wang, Shih-Tsung Kang, Ching-Fang Yu, Fang-Hsin Chen, Chi-Shiun Chiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-06-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-024-54432-y
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