In Silico ADME Prediction and Molecular Docking of 1,2,3-Triazole-based Compounds Against Human Aromatase Cytochrome P450

Objective: Inhibition of the human aromatase cytochrome P450 enzyme has been emphasized as being an efficient mechanism for reducing high estrogen levels in the treatment of breast cancer.  Methods: Molecular docking and in silico ADME predictions were performed for a set of 1,2,3-triazole-based com...

Full description

Bibliographic Details

Main Authors:	Ola Nosseir, Yasmin Syam, Alaa Hashim, Radwan El-Haggar, Manal Anwar, Wafaa Zaghary
Format:	Artigo
Language:	Inglês
Published:	Helwan University, Faculty of Pharmacy 2023-10-01
Series:	Journal of Advanced Pharmacy Research
Subjects:	In Silico ADME Molecular Docking Triazole Aromatase Inhibitors
Online Access:	https://aprh.journals.ekb.eg/article_323954_356e980eb70082445ee8572ac95755e1.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!