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Sub-Inhibitory Concentrations of Mupirocin Strongly Inhibit Alpha-Toxin Production in High-Level Mupirocin-Resistant MRSA by Down-Regulating agr, saeRS, and sarA

Mupirocin, a topical antibiotic, has been utilized for decades to treat Staphylococcus aureus skin infections, as well as to decolonize patients at risk of methicillin-resistant S. aureus (MRSA) infection. The aims of this study were to investigate the expression of α-toxin (encoded by the hla gene)...

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書誌詳細
主要な著者: Ye Jin, Meilan Li, Yongpeng Shang, Li Liu, Xiaofei Shen, Zhihui Lv, Zhihao Hao, Jingjing Duan, Yang Wu, Chun Chen, Jingye Pan, Fangyou Yu
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018-05-01
シリーズ:Frontiers in Microbiology
主題:
オンライン・アクセス:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00993/full
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