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Structural and functional insights into endoglin ligand recognition and binding.

Endoglin, a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells, is a component of the transforming growth factor (TGF)-β receptor complex and is implicated in a dominant vascular dysplasia known as hereditary hemorrhagic telangiectasia as well...

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Autors principals: Aaron Alt, Laura Miguel-Romero, Jordi Donderis, Mikel Aristorena, Francisco J Blanco, Adam Round, Vicente Rubio, Carmelo Bernabeu, Alberto Marina
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3275592?pdf=render
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