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Ancient mechanisms for the evolution of the bicoid homeodomain's function in fly development

The ancient mechanisms that caused developmental gene regulatory networks to diversify among distantly related taxa are not well understood. Here we use ancestral protein reconstruction, biochemical experiments, and developmental assays of transgenic animals carrying reconstructed ancestral genes to...

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Principais autores: Qinwen Liu, Pinar Onal, Rhea R Datta, Julia M Rogers, Urs Schmidt-Ott, Martha L Bulyk, Stephen Small, Joseph W Thornton
格式: Artigo
语言:Inglês
出版: eLife Sciences Publications Ltd 2018-10-01
丛编:eLife
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在线阅读:https://elifesciences.org/articles/34594
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