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MnO2 and roflumilast-loaded probiotic membrane vesicles mitigate experimental colitis by synergistically augmenting cAMP in macrophage

Abstract Background Ulcerative colitis (UC) is one chronic and relapsing inflammatory bowel disease. Macrophage has been reputed as one trigger for UC. Recently, phosphodiesterase 4 (PDE4) inhibitors, for instance roflumilast, have been regarded as one latent approach to modulating macrophage in UC...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chengjun Song, Jiamin Wu, Jinhui Wu, Fangyu Wang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2024-05-01
Rangatū:Journal of Nanobiotechnology
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12951-024-02558-6
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