Activation of liver X receptor plays a central role in antiviral actions of 25-hydroxycholesterol

Production of 25-hydroxycholesterol (25HC), a potent inhibitor of viral infection, is catalyzed by cholesterol 25-hydroxylase (CH25H). We previously reported that 25HC induced CH25H expression in a liver X receptor (LXR)-dependent manner, implying that LXR can play an important role in antiviral inf...

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Autors principals:	Ying Liu, Zhuo Wei, Ye Zhang, Xingzhe Ma, Yuanli Chen, Miao Yu, Chuanrui Ma, Xiaoju Li, Youjia Cao, Jian Liu, Jihong Han, Xiaoxiao Yang, Yajun Duan
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2018-12-01
Col·lecció:	Journal of Lipid Research
Matèries:	cholesterol 25-hydroxylase 25-hydroxycholesterol-3-sulfate interferon γ
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0022227520341547
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