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In Vivo Emergence of UL56 C325Y Cytomegalovirus Resistance to Letermovir in a Patient with Acute Myeloid Leukemia after Hematopoietic Cell Transplantation

CMV associated tissue-invasive disease is associated with a considerable risk of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Recently, the terminase inhibitor letermovir (LMV) has been approved for prophylaxis of CMV infection in HSCT. We hereby report a...

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Principais autores: Jochen J Frietsch, Detlef Michel, Thomas Stamminger, Friederike Hunstig, Sebastian Birndt, Ulf Schnetzke, Sebastian Scholl, Andreas Hochhaus, Inken Hilgendorf
Format: Artigo
Sprog:Inglês
Udgivet: PAGEPress Publications 2019-01-01
Serier:Mediterranean Journal of Hematology and Infectious Diseases
Fag:
Cytomegalovirus
hematopoietic stem cell transplantation
reactivation
letermovir
Online adgang:https://www.mjhid.org/index.php/mjhid/article/view/3708
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