NK cell-related genes-driven novel molecular subtyping and prognostic signatures for Wilms tumor: uncovering the therapeutic potential of TGX-221 and biomarker role of HS2ST1

BackgroundWilms tumor (WT) lacks precise molecular subtyping tools, which limits the development of personalized therapies. To address this issue, we investigated whether NK cell-related genes (NKGs) could refine the molecular subtyping of WT, aiming to identify novel therapeutic strategies.MethodsC...

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Autori principali:	Peng Hong, Zaihong Hu, Jie Lin, Kongkong Cui, Zhiqiang Gao, Xiaomao Tian, Tao Lin, Qinlin Shi, Guanghui Wei
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-08-01
Serie:	Frontiers in Oncology
Soggetti:	Wilms tumor natural killer cells molecular subtyping prognostic signatures TGX-221 HS2ST1
Accesso online:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1593011/full
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