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Nanostructured Lipid Carriers Loaded with Donepezil for Nose-to-Brain Targeting

<b>Background/Objectives:</b> The oral administration of donepezil has been shown to have common side effects due to systemic drug delivery, with fluctuations in blood and brain donepezil concentrations. Therefore, we obtained nanostructured lipid carriers loaded with donepezil (donepezil–NLC) for n...

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Autors principals: Isabelly Fernanda Ferraz de Souza, Rodrigo Vicentino Placido, Maria Júlia Placido, Letícia Carvalho Rocha, Rudy Bonfilio, Vanessa Bergamin Boralli, André Luís Morais Ruela, Gislaine Ribeiro Pereira
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2026-04-01
Col·lecció:Pharmaceutics
Matèries:
Alzheimer’s disease
donepezil
nanostructured lipid carriers
nose to brain
pharmacokinetics
intranasal administration
Accés en línia:https://www.mdpi.com/1999-4923/18/5/541
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