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Integrative analysis of plasma small-molecule and gut-microbiome markers of sarcopenia in a pilot study within an Indian cohort

Abstract Sarcopenia, the age-associated decline in muscle mass and strength, is influenced by metabolic, inflammatory, and microbiome-related factors. However, integrative analyses combining these dimensions remain limited. This study applies a multi-omics workflow to identify plasma metabolite, lip...

Deskribapen osoa

Gorde:
Egile Nagusiak: Maroof Athar Hashmi, Shivangi Verma, Raviswamy G. H. Math, Sneha Muralidharan, Gautham Pranesh, M. P. Sahana, Nivedita Hariharan, Madhusudan N. C., Vijay Kamath, Vishwanath Yaligod, Santosh Angadi Hiremath, Abhijit Jawali, Tatarao Maddipati, Sindhulina Chandrasingh, Asha Thomas, Niranjan Mallnaik, V. C. Shanmuganand, Carolin Elizabeth George, Alexander Thomas, Tarini Shankar Ghosh, Arvind Ramanathan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2026-01-01
Saila:Scientific Reports
Gaiak:
Sarcopenia
Metabolomics
Lipidomics
Gut microbiome
Biomarkers
Machine learning
Sarrera elektronikoa:https://doi.org/10.1038/s41598-026-35476-8
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