Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus

Abstract Background The rapid emergence of multiple drug-resistant (MDR) bacterial pathogens and the lack of a novel antibiotic pipeline pose a serious threat to global healthcare. The limited number of established targets further restricts the identification of novel antibiotics to treat life-threa...

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Bibliografische Detailangaben

Hauptverfasser:	Maria Sultan, Maria Razzaq, Joohyun Lee, Shreyasi Das, Shrute Kannappan, Vinod Kumar Subramani, Wanki Yoo, Truc Kim, Hye-Ra Lee, Akhilesh K. Chaurasia, Kyeong Kyu Kim
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-02-01
Schriftenreihe:	Journal of Biomedical Science
Schlagworte:	S. aureus USA300 G-quadruplex G4 ligands N-methyl mesoporphyrin IX (NMM) Division cell wall dcw cluster
Online-Zugang:	https://doi.org/10.1186/s12929-024-01109-3
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