Integration of genetic evidence to identify approved drug targets
Abstract Background Drugs targeting genes supported by human genetic evidence are more likely to succeed in clinical trials. While previous approaches have benchmarked individual methods such as genome-wide association studies (GWAS), rare variant burden testing, and quantitative trait locus (QTL)-i...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2026-07-01
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| Schriftenreihe: | Genome Medicine |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s13073-026-01689-9 |
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