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Cross-reactive antibodies against Langat virus protect mice from lethal tick-borne encephalitis virus infection

IntroductionNaturally attenuated Langat virus (LGTV) and highly pathogenic tick-borne encephalitis virus (TBEV) share antigenically similar viral proteins and are grouped together in the same flavivirus serocomplex. In the early 1970s, this has encouraged the usage of LGTV as a potential live attenu...

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Principais autores: Mareike Kubinski, Jana Beicht, Isabel Zdora, Giulietta Saletti, Magdalena Kircher, Monique Petry-Gusmag, Imke Steffen, Christina Puff, Klaus Jung, Wolfgang Baumgärtner, Guus F. Rimmelzwaan, Albert D. M. E. Osterhaus, Chittappen Kandiyil Prajeeth
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-02-01
Serier:Frontiers in Immunology
Fag:
TBEV
immunity
cross-reactivity
LGTV
CNS
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1134371/full
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