Developing an eVLP mRNA vaccine for respiratory syncytial virus with enhanced pre-fusion targeting humoral responses

ABSTRACT Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease (LRTD) in infants, the elderly, and immunocompromised individuals. In this study, we leveraged the innovative EABR (ESCRT- and ALIX-binding region) vaccine technology to develop a pre-fusion (Pre-F)-base...

Description complète

Détails bibliographiques

Auteurs principaux:	Lei Sun, Mengting Huang, Simin Feng, Wei Zhang, Yun Quan, Ruyi Chen, Yupeng Yang, Haidong Xu, Wansheng Li, Qianyu Pan, Xinwen Chen, Danyang Zhang, Bin Yuan, Jincun Zhao, Zhongfang Wang, Jinzhong Lin, Wei Peng, Martin Ludlow, Qiong Zhang
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology 2025-10-01
Collection:	Journal of Virology
Sujets:	mRNA vaccine respiratory syncytial virus EABR eVLPs immune responses
Accès en ligne:	https://journals.asm.org/doi/10.1128/jvi.01209-25
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!