Beneficial effects of Oltipraz, nuclear factor - erythroid – 2 - related factor 2 (Nrf2), on renal damage in unilateral ureteral obstruction rat model

ABSTRACT Introduction: We investigated whether Oltipraz (OPZ) attenuated renal fibrosis in a unilateral ureteral obstruction (UUO) rat model. Materials and Methods: We randomly divided 32 rats into four groups, each consisting of eight animals as follows: Rats in group 1 underwent a sham operation...

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Hlavní autoři:	Emre Can Polat, Huseyin Besiroglu, Levent Ozcan, Alper Otunctemur, Ahmet Tugrul Eruyar, Adnan Somay, Nurver Ozbay, Mustafa Cekmen, Ceyla Eraldemir, Emin Ozbek
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Sociedade Brasileira de Urologia
Edice:	International Brazilian Journal of Urology
Témata:	Oltipraz [Supplementary Concept] Renal Insufficiency Ureter
On-line přístup:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382018000601243&lng=en&tlng=en
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