Plasma proteins mediate the effects of the gut microbiota on the development of head and neck cancer: a two-sample and mediated Mendelian randomized study

Abstract Background Although previous observational studies have highlighted a possible association between the gut microbiota (GM) and head and neck cancer (HNC), the causal relationships remain unclear, particularly regarding the role of plasma proteins as potential mediators. Clarifying these con...

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Detalhes bibliográficos

Principais autores:	Jin-Hui Rao, Wen-Da Zhang, Cheng-Peng Zha, Min-Yue Zhang, Yu-Jie Xing, Zai-Hui Wang, Jun-Xian Yu, Dong-Yan He, Chuan-Zheng Sun, Lei Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2025-02-01
coleção:	Discover Oncology
Assuntos:	Head and neck cancer Gut microbiota Plasma proteins Causal inference Mendelian randomization
Acesso em linha:	https://doi.org/10.1007/s12672-025-01983-9
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