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Volume-Associated Clinical and Histopathological Effects of Intranasal Instillation in Syrian Hamsters: Considerations for Infection and Therapeutic Studies

Syrian hamsters are a key animal model of SARS-CoV-2 and other respiratory viruses and are useful for the evaluation of associated medical countermeasures. Delivery of an infectious agent or intervention to the respiratory tract mirrors natural routes of exposure and allows for the evaluation of cli...

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Principais autores: Catalina Forero, Jana M. Ritter, Josilene Nascimento Seixas, JoAnn D. Coleman-McCray, Marie Brake, Jillian A. Condrey, Cassandra Tansey, Stephen R. Welch, Sarah C. Genzer, Jessica R. Spengler
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-08-01
Series:Pathogens
Assuntos:
Syrian hamster
animal model
respiratory virus model
intranasal instillation
intranasal inoculation
histopathology
Acceso en liña:https://www.mdpi.com/2076-0817/11/8/898
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