ICEBERG study: an indirect adjusted comparison estimating the long-term benefit of esketamine nasal spray when compared with routine treatment of treatment resistant depression in general psychiatry

BackgroundTreatment resistant depression (TRD) affects 10–30% of patients with major depressive disorder. In 4-week trials, esketamine nasal spray (NS) was efficacious vs. placebo when both were initiated in addition to a new selective serotonin or serotonin norepinephrine reuptake inhibitor. Howeve...

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Principais autores:	Albino J. Oliveira-Maia, Joachim Morrens, Benoit Rive, Yordan Godinov, Jedelyn Cabrieto, Nolen Perualila, Sebastien Barbreau, Siobhán Mulhern-Haughey
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-10-01
Colecção:	Frontiers in Psychiatry
Assuntos:	treatment resistant depression real-world evidence indirect comparison remission response esketamine nasal spray
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1250980/full
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