Mycobacterium tuberculosis-Specific T Cell Functional, Memory, and Activation Profiles in QuantiFERON-Reverters Are Consistent With Controlled Infection

Reversion of immune sensitization tests for Mycobacterium tuberculosis (M.tb) infection, such as interferon-gamma release assays or tuberculin skin test, has been reported in multiple studies. We hypothesized that QuantiFERON-TB Gold (QFT) reversion is associated with a decline of M.tb-specific func...

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Autors principals:	Cheleka A. M. Mpande, Pia Steigler, Tessa Lloyd, Virginie Rozot, Boitumelo Mosito, Constance Schreuder, Timothy D. Reid, Nicole Bilek, Morten Ruhwald, Jason R. Andrews, Mark Hatherill, Francesca Little, Thomas J. Scriba, Elisa Nemes
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-08-01
Col·lecció:	Frontiers in Immunology
Matèries:	QuantiFERON reversion memory T cell donor unrestricted T cells innate immune response Mycobacterium tuberculosis infection
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.712480/full
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