Mosaic results after preimplantation genetic testing for aneuploidy may be accompanied by changes in global gene expression

Aneuploidy in preimplantation embryos is a major cause of human reproductive failure. Unlike uniformly aneuploid embryos, embryos diagnosed as diploid-aneuploid mosaics after preimplantation genetic testing for aneuploidy (PGT-A) can develop into healthy infants. However, the reason why these embryo...

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Библиографические подробности

Главные авторы:	A. Martin, A. Mercader, F. Dominguez, A. Quiñonero, M. Perez, R. Gonzalez-Martin, A. Delgado, A. Mifsud, A. Pellicer, M. J. De Los Santos
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-04-01
Серии:	Frontiers in Molecular Biosciences
Предметы:	embryonic mosaicism RNA sequencing preimplantation genetic testing for aneuploidy next-generation sequencing blastomere cell cycle
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fmolb.2023.1180689/full
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