Targeting class IA PI3K isoforms selectively impairs cell growth, survival, and migration in glioblastoma.

The phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is frequently activated in human cancer and plays a crucial role in glioblastoma biology. We were interested in gaining further insight into the potential of targeting PI3K isoforms as a novel anti-tumor approach i...

Descripción completa

Detalles Bibliográficos

Autores principales:	Katrin Höland, Danielle Boller, Christian Hagel, Silvia Dolski, András Treszl, Olivier E Pardo, Paulina Cwiek, Fabiana Salm, Zaira Leni, Peter R Shepherd, Beata Styp-Rekowska, Valentin Djonov, André O von Bueren, Karl Frei, Alexandre Arcaro
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2014-01-01
Colección:	PLoS ONE
Acceso en línea:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094132&type=printable
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!