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Catalytic DxD motif caged in Asx-turn and Met–aromatic interaction attenuates the pathogenic glycosylation of SseK2/NleB2 effectors

Abstract Pathogenic bacteria encode virulent glycosyltransferases that conjugate various glycans onto host crucial proteins, which allows adhesion to mammalian cells and modulates host cellular processes for pathogenesis. Escherichia coli NleB1, Citrobacter rodentium NleB, and Salmonella enterica Ss...

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Bibliografische gegevens
Hoofdauteurs: Eunhee Koh, Uijin Kim, Hyun-Soo Cho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2022-11-01
Reeks:Scientific Reports
Online toegang:https://doi.org/10.1038/s41598-022-22803-y
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