In Silico Approach Using Free Software to Optimize the Antiproliferative Activity and Predict the Potential Mechanism of Action of Pyrrolizine-Based Schiff Bases

In the current study, a simple in silico approach using free software was used with the experimental studies to optimize the antiproliferative activity and predict the potential mechanism of action of pyrrolizine-based Schiff bases. A compound library of 288 Schiff bases was designed based on compou...

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Auteurs principaux:	Faisal A. Almalki, Ashraf N. Abdalla, Ahmed M. Shawky, Mahmoud A. El Hassab, Ahmed M. Gouda
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2021-06-01
Collection:	Molecules
Sujets:	pyrrolizine antiproliferative cell cycle analysis apoptosis pharmacophore search docking study
Accès en ligne:	https://www.mdpi.com/1420-3049/26/13/4002
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