Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women

IntroductionChronic immune activation is a hallmark of human immunodeficiency virus (HIV) infection that significantly impacts disease pathogenesis. However, in-depth studies characterizing the immunological landscape of the ectocervix during chronic HIV infection remain scarce despite the importanc...

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Autores principales:	Mathias Franzén Boger, Vilde Kaldhusdal, Anna Pascual-Reguant, Sandy Kroh, Ralf Uecker, Adam D. Burgener, Julie Lajoie, Kenneth Omollo, Joshua Kimani, Keith R. Fowke, Anja E. Hauser, Annelie Tjernlund, Kristina Broliden
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2024-12-01
Colección:	Frontiers in Immunology
Materias:	HIV spatial transcriptomics multi-epitope ligand cartography mucosal immunology T cells B cells
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1483346/full
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