Protective Effect of Fenofibrate on Oxidative Stress-Induced Apoptosis in Retinal–Choroidal Vascular Endothelial Cells: Implication for Diabetic Retinopathy Treatment

Diabetic retinopathy (DR) is an important microvascular complication of diabetes and one of the leading causes of blindness in developed countries. Two large clinical studies showed that fenofibrate, a peroxisome proliferator-activated receptor type α (PPAR-α) agonist, reduces DR progression. We eva...

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Detalhes bibliográficos

Principais autores:	Ying-Jung Hsu, Chao-Wen Lin, Sheng-Li Cho, Wei-Shiung Yang, Chung-May Yang, Chang-Hao Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-08-01
Colecção:	Antioxidants
Assuntos:	apoptosis diabetic retinopathy fenofibrate oxidative stress thioredoxin
Acesso em linha:	https://www.mdpi.com/2076-3921/9/8/712
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