Transcriptomic rewiring of the JAK–STAT pathway in circulating CD4+CLA+ and CD4+ naïve T cells from patients with atopic dermatitis and psoriasis

BackgroundSkin-homing cutaneous lymphocyte-associated antigen (CLA)-expressing T cells play a key role in the pathogenesis of atopic dermatitis (AD) and psoriasis (Ps). We aimed to characterize the transcriptomic and epigenetic profiles of circulating CD4+CLA+ and CD4+ naïve T cells from patients wi...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Martin Pook, Regina Maruste, Peep Kolberg, Kaur Alasoo, Tõnis Org, Liisi Raam, Anu Remm, Dario Greco, Antonio Federico, Külli Kingo, Kai Kisand, Ana Rebane
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2026-04-01
Reeks:	Frontiers in Immunology
Onderwerpen:	ATAC sequencing atopic dermatitis CD4+ T cells cutaneous lymphocyte-associated antigen psoriasis
Online toegang:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1782684/full
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!