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Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Abstract Aminoglycoside antibiotic‐induced sensorineural hearing loss (SNHL) is a common sensory disorder that requires the development of prophylactic and therapeutic interventions. Lycium barbarum glycopeptide (LBGP) is a peptidoglycan isolated and purified from Lycium barbarum polysaccharides tha...

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Principais autores: Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2025-08-01
coleção:Advanced Science
Assuntos:
Lycium barbarum glycopeptide
P‐chlorophenylalanine
sensorineural hearing loss
tryptophan hydroxylase
tryptophan metabolism
Acesso em linha:https://doi.org/10.1002/advs.202405850
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