Preclinical comparison of [177Lu]Lu-rhPSMA-10.1 and [177Lu]Lu-rhPSMA-10.2 for endoradiotherapy of prostate cancer: biodistribution and dosimetry studies

Abstract Background Radiohybrid PSMA-targeted ligands (rhPSMA) have been introduced as a novel platform for theranostic applications. Among a variety of rhPSMA-ligands developed for radioligand therapy, two stereoisomers [177Lu]Lu-rhPSMA-10.1 and -10.2 have been synthesized and initially characteriz...

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Auteurs principaux:	Alexander Wurzer, Francesco De Rose, Sebastian Fischer, Markus Schwaiger, Wolfgang Weber, Stephan Nekolla, Hans-Jürgen Wester, Matthias Eiber, Calogero D’Alessandria
Format:	Artigo
Langue:	Inglês
Publié:	SpringerOpen 2024-02-01
Collection:	EJNMMI Radiopharmacy and Chemistry
Sujets:	Prostate cancer Radioligand therapy Radiohybrid rhPSMA PSMA
Accès en ligne:	https://doi.org/10.1186/s41181-024-00246-2
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