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Efficacy and safety of neoadjuvant therapy combined with immunotherapy in MMR‑proficient/microsatellite stable non‑metastatic rectal cancer: a systematic review and meta‑analysis

Abstract Objective To comprehensively evaluate the efficacy and safety of neoadjuvant therapy combined with immunotherapy in patients with MMR-proficient/microsatellite stable (pMMR/MSS) non-metastatic rectal cancer. Methods Major databases, including PubMed, Web of Science, Cochrane Library, Embase...

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Principais autores: Yuegang Li, Chengcheng Han, Jianqiang Tang
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2025-12-01
Serier:Journal of Cancer Research and Clinical Oncology
Fag:
Neoadjuvant therapy
Immunotherapy
Rectal cancer
pMMR/MSS
Meta-analysis
Online adgang:https://doi.org/10.1007/s00432-025-06387-4
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