Precisely Tailoring Molecular Structure of Doxorubicin Prodrugs to Enable Stable Nanoassembly, Rapid Activation, and Potent Antitumor Effect

Background: Achieving a balance between stable drug loading/delivery and on-demand drug activation/release at the target sites remains a significant challenge for nanomedicines. Carrier-free prodrug nanoassemblies, which rely on the design of prodrug molecules, offer a promising strategy to optimize...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Chengcheng Feng, Yuting Wang, Jiaxu Xu, Yanzi Zheng, Wenhu Zhou, Yuequan Wang, Cong Luo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-12-01
coleção:	Pharmaceutics
Assuntos:	molecular design doxorubicin prodrug nanoassembly drug delivery drug release
Acesso em linha:	https://www.mdpi.com/1999-4923/16/12/1582
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!