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Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp.

ABSTRACT Cefiderocol, a siderophore-cephalosporine conjugate antibiotic, shows promise as a therapeutic option for carbapenem-resistant (CR) Acinetobacter infections. While resistance has already been reported in A. baumannii, combination therapies with avibactam or sulbactam reduce MICs of cefidero...

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Furkejuvvon:
Váldodahkkit: Olivia Wong, Vyanka Mezcord, Christina Lopez, German Matias Traglia, Fernando Pasteran, Marisel R. Tuttobene, Alejandra Corso, Marcelo E. Tolmasky, Robert A. Bonomo, María Soledad Ramirez
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Microbiology 2024-10-01
Ráidu:Microbiology Spectrum
Fáttát:
Acinetobacter
antagonism
cefiderocol
antimicrobial susceptibility testing (AST)
avibactam
sulbactam
Liŋkkat:https://journals.asm.org/doi/10.1128/spectrum.00930-24
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