Transcriptomic profile of RNA pseudouridine modification as a biomarker for cellular senescence associated with survival outcomes in colorectal cancer

Abstract Background Colorectal cancer (CRC) is considered as an age-related disease, and cellular senescence (CS) plays a crucial role in cancer development and progression. Previous studies have shown the role of epigenetic changes in aging and cancer development, but the role of RNA pseudouridine...

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Auteurs principaux:	Yingguo Gan, Ze Yuan, Jingrong Weng, Mingzhe Huang, Tuoyang Li, Yuanhui Wu, Kaixin Lin, Junyi Han, Xuan Li, Haotian Liu, Zixiao Wan, Ziming Li, Zhenghua Chen, Ji Cui, Yanxin Luo, Meijin Huang, Huichuan Yu, Jinxin Lin
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2025-02-01
Collection:	BMC Biology
Sujets:	RNA Ψ modification Cellular senescence Colorectal cancer Psi Score
Accès en ligne:	https://doi.org/10.1186/s12915-025-02170-6
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