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Host biomarkers and parasite biomass are associated with severe malaria in Mozambican children: a case–control study

Abstract Severe pediatric malaria remains a pressing global health issue. Laboratory parameters may provide early risk and severity stratification for better disease management, beyond current clinical severity scores. This study aimed to identify host biomarkers of immune and endothelial activation...

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Autori principali: Rosauro Varo, Antonio Sitoe, Lola Madrid, Pedro Aide, Inocencia Cuamba, Anélsio Cossa, Chenjerai Jairoce, Diana Barrios, Xavier Martiáñez-Vendrell, Núria Balanza, Pau Cisteró, Dan Ouchi, Llorenç Quintó, Valerie M. Crowley, Himanshu Gupta, Kevin C. Kain, Alfredo Mayor, Quique Bassat
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-04-01
Serie:Scientific Reports
Soggetti:
Severe malaria
Risk-stratification
Pediatric
HRP-2
Endothelial activation
Host biomarkers
Accesso online:https://doi.org/10.1038/s41598-025-98154-1
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