Multiple transcription auto regulatory loops can act as robust oscillators and decision-making motifs

Response time decides how fast a gene can react against an external signal at the transcription level in a signalling cascade. The steady state protein levels of the responding genes decide the coupling between two consecutive members of a signalling cascade. A negative autoregulatory loop (NARL) pr...

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Bibliografiska uppgifter

Huvudupphov:	Rajamanickam Murugan, Gabriel Kreiman
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Association for the Advancement of Science (AAAS) 2022-01-01
Serie:	Computational and Structural Biotechnology Journal
Ämnen:	Transcriptional regulation Auto-regulatory networks Biophysical theory and computational modelling Robustness Gene expression control Molecular fluctuations
Länkar:	http://www.sciencedirect.com/science/article/pii/S2001037022003993
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