Platelet‐Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism

Abstract Lipid metabolism reprogramming stands as a fundamental hallmark of cancer cells. Unraveling the core regulators of lipid biosynthesis holds the potential to find promising therapeutic targets in pancreatic ductal adenocarcinoma (PDAC). Here, it is demonstrated that platelet‐derived growth f...

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Автори:	Yin‐Hao Shi, Zhi‐De Liu, Ming‐Jian Ma, Guang‐Yin Zhao, Ying‐Qin Zhu, Jie‐Qin Wang, Yang‐Yin‐Hui Yu, Xi‐Tai Huang, Jing‐Yuan Ye, Fu‐Xi Li, Xi‐Yu Wang, Qiong‐Cong Xu, Xiao‐Yu Yin
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Wiley 2024-10-01
Серія:	Advanced Science
Предмети:	lipid metabolism metastasis PDAC PDGFC SREBP1
Онлайн доступ:	https://doi.org/10.1002/advs.202407069
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