Classification of pediatric soft and bone sarcomas using DNA methylation-based profiling

Abstract Pediatric sarcomas present heterogeneous morphology, genetics and clinical behavior posing a challenge for an accurate diagnosis. DNA methylation is an epigenetic modification that coordinates chromatin structure and regulates gene expression, determining cell type and function. DNA methyla...

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主要な著者:	Felipe Luz Torres Silva, Mayara Ferreira Euzébio, Juliana Silveira Ruas, Mayra Troiani Franco, Alejandro Enzo Cassone, Thais Junqueira, Danielle Ribeiro Lucon, Izilda Aparecida Cardinalli, Luis Henrique Pereira, Priscila Pini Zenatti, Patricia Yoshioka Jotta, Mariana Maschietto
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-11-01
シリーズ:	BMC Cancer
主題:	Pediatric sarcomas Soft and bone sarcomas Molecular classification DNA methylation Copy number alteration
オンライン･アクセス:	https://doi.org/10.1186/s12885-024-13159-9
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