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Safety and efficacy of mirikizumab as induction and maintenance for inflammatory bowel disease in adult patients: a systematic review and meta-analysis

Abstract Background Mirikizumab, a monoclonal antibody targeting interleukin-23 (IL-23), was studied for adult patients with moderate-to-severe inflammatory bowel disease (IBD). However, conflicting evidence exists on its safety, efficacy and optimal dosing strategy. Aim To evaluate the safety and e...

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Principais autores: Maryam Falah, Leen Alhamd, Fatma Bayoumi, Aisha Allah Diwaya, Enas Taha, Lamia Alkodami, Riham Alsutaif, Bushra Mohandes, Idris Sula, Muhammad Candragupta Jihwaprani, Fathiya El-Raey
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2026-05-01
Serier:The Egyptian Journal of Internal Medicine
Fag:
Mirikizumab
IBD
Crohn’s disease
Ulcerative colitis
IL-23
Online adgang:https://doi.org/10.1186/s43162-026-00643-w
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