GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo
Abstract Background Insulin secretion from the pancreatic β-cell is finely modulated by different signals to allow an adequate control of glucose homeostasis. Incretin hormones such as glucagon-like peptide-1 (GLP-1) act as key physiological potentiators of insulin release through binding to the G p...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2021-03-01
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| Schriftenreihe: | BMC Biology |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s12915-021-00966-w |
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