Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability

The fidelity of chromosome segregation in mitosis is safeguarded by the precise regulation of kinetochore microtubule (k-MT) attachment stability. Previously, we demonstrated that Cyclin A/Cdk1 destabilizes k-MT attachments to promote faithful chromosome segregation. Here, we use quantitative phosph...

Descripción completa

Detalles Bibliográficos

Autores principales:	Ana Maria G Dumitru, Scott F Rusin, Amber E M Clark, Arminja N Kettenbach, Duane A Compton
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2017-11-01
Colección:	eLife
Materias:	mitosis kinetochore Plk1 microtubule cyclin dependent kinase
Acceso en línea:	https://elifesciences.org/articles/29303
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!