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Nanopore sequencing-based genotyping suggested an association between CYP2D6 function and susceptibility to anxiety and depression

Abstract Objective CYP2D6 activity has been inconsistently associated with anxious and depressive personality traits. The inconsistency may stem from limitations of targeted genotyping, employed in most previous studies, leading to undetected errors in metabolic classification. Using a nanopore sequ...

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Principais autores: Eng Wee Chua, Harsheni Karunanathie, Kevina Yanasegaran, Simran Maggo, Ping Siu Kee, Martin Kennedy, Mohd Rizal Abdul Manaf, Pei Yuen Ng
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-02-01
Serier:BMC Research Notes
Fag:
CYP2D6
Anxiety
Depression
Nanopore sequencing
Online adgang:https://doi.org/10.1186/s13104-025-07156-9
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