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Ligand-based drug design and molecular docking simulation studies of some novel anticancer compounds on MALME-3M melanoma cell line

Abstract Background Melanoma cancer causes serious health problem worldwide because of its rapid invasion to other organs and lack of satisfactory chemotherapy. The pGI50 anticancer activity values of 70 compounds from the NCI (National Cancer Institute) on MALME-3M cell line was modeled to describe...

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Hlavní autoři: Abdullahi Bello Umar, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba
Médium: Artigo
Jazyk:Inglês
Vydáno: SpringerOpen 2021-01-01
Edice:Egyptian Journal of Medical Human Genetics
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On-line přístup:https://doi.org/10.1186/s43042-020-00126-9
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